NIOSH Pocket Guide

Acetylsalicyclic acid

CAS

50-78-2

CH3COOC6H4COOH

RTECS

VO0700000

Synonyms & Trade Names


o-Acetoxybenzoic acid, 2-Acetoxybenzoic acid, Aspirin

DOT ID & Guide
 

Exposure
Limits

NIOSH REL: TWA 5 mg/m3
OSHA PEL†: none
IDLH

N.D. 

Conversion
Physical Description
 

Odorless, colorless to white, crystal-line powder. [aspirin] [Note: Develops the vinegar-like odor of acetic acid on contact with moisture.]

MW: 180.2
 
BP: 284°F (Decomposes)
 
MLT: 275°F
 
Sol(77°F): 0.3%
 
VP: 0 mmHg (approx)
 
IP: NA
 

 
Sp.Gr: 1.35
 
Fl.P: NA
 
UEL: NA
 
LEL: NA
 
MEC: 40 g/m3
 
Combustible Powder; explosion hazard if dispersed in air.
Incompatibilities & Reactivities


Solutions of alkali hydroxides or carbonates, strong oxidizers, moisture [Note: Slowly hydrolyzes in moist air to salicyclic & acetic acids.]

Personal Protection & Sanitation


Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: No recommendation
Change: Daily
Provide: Eyewash, Quick drench
 

First Aid


Eye: Irrigate immediately
Skin: Soap wash
Breathing: Respiratory support
Swallow: Medical attention immediately
 

Respirator Recommendations

Not available.
 

Exposure Routes

inhalation, ingestion, skin and/or eye contact

Symptoms

Irritation eyes, skin, upper respiratory system; increased blood clotting time; nausea, vomiting; liver, kidney injury

Target Organs



 

Cancer Site

Eyes, skin, respiratory system, blood, liver, kidneys

 

Fuente: U.S. Department of Health and Human Services

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